Monday, May 12


Gran's new lease of life thanks to mobility scooter
Lancaster Today
Despite living with Multiple Sclerosis, grandmother Brenda Escreet continues to attend numerous music festivals and gigs, support several charities and have ‘biking’ freedom outdoors thanks to her mobility scooter.

Mouse Studies Reveal Promising Vitamin D-Based Treatment for MS
 A diagnosis of multiple sclerosis (MS) is a hard lot. Patients typically get the diagnosis around age 30 after experiencing a series of neurologicalproblems. In search of a better option for MS patients, a team of University of Wisconsin-Madison biochemists has discovered a promising vitamin D-based treatment that can halt -- and even reverse -- the course of the disease in a mouse model of MS. The treatment involves giving mice that exhibit MS symptoms a single dose of calcitriol, the active hormone form of vitamin D, followed by ongoing vitamin D supplements through the diet. The protocol is described in a scientific article that was published online in August in the Journal of Neuroimmunology. "All of the animals just got better and better, and the longer we watched them, the more neurological function they regained," says biochemistry professor Colleen Hayes, who led the study.

Multiple Sclerosis Therapeutics to 2019 - Treatment Diversification, Increasing Efficacy, and Pipeline Innovation Combine to Drive Growth

Biogen: All Reasons For Bulls To Be Happy


Tysabri (Natalizumab) treatment decreases serum IgM and IgG levels in multiple sclerosis patients
   Rebecca C Selter, Viola Biberacher, Verena Grummel, Dorothea Buck,
   Christian Eienbroker, Wolfgang H Oertel, Achim Berthele, Bjorn
   Tackenberg, and Bernhard Hemmer
   Multiple Sclerosis Journal. 2013;  19(11): p. 1454-1461

Expression of cathepsins S and D signals a distinctive biochemical trait in CD34+ hematopoietic stem cells of relapsing–remitting multiple sclerosis patients 
   Sabata Martino, Simona Montesano, Ilaria di Girolamo, Roberto Tiribuzi,
   Maria Di Gregorio, Antonio Orlacchio, Alessandro Datti, Paolo
   Calabresi, Paola Sarchielli, and Aldo Orlacchio
   Multiple Sclerosis Journal. 2013;  19(11): p. 1443-1453

Saskatchewan trial for MS liberation therapy cancelled, citing lack of volunteers

Observational case-control study of the prevalence of chronic cerebrospinal venous insufficiency in multiple sclerosis: results from the CoSMo study 
   G Comi, MA Battaglia, A Bertolotto, M Del Sette, A Ghezzi, G
   Malferrari, M Salvetti, MP Sormani, L Tesio, E Stolz, P Zaratin, G
   Mancardi, and   the CoSMo Collaborative Study Group
   Multiple Sclerosis Journal. 2013;  19(11): p. 1508-1517 Open Access

Circulating dendritic cells of multiple sclerosis patients are proinflammatory and their frequency is correlated with MS-associated genetic risk factors 
   Kristof Thewissen, Amber H Nuyts, Nathalie Deckx, Bart Van Wijmeersch,
   Guy Nagels, Marie D'hooghe, Barbara Willekens, Patrick Cras, Bert O
   Eijnde, Herman Goossens, Viggo FI Van Tendeloo, Piet Stinissen, Zwi N
   Berneman, Niels Hellings, and Nathalie Cools
   Multiple Sclerosis Journal. published 23 September 2013,

Higher Relative Risk for Multiple Sclerosis in a Pediatric and Adolescent Diabetes Population: Analysis From DPV Data Base
   Susanne Bechtold, Astrid Blaschek, Klemens Raile, Axel Dost, Clemens
   Freiberg, Meik Askenas, Elke Frohlich-Reiterer, Esther Molz, and
   Reinhard W. Holl
   Diabetes Care. published 23 September 2013, 10.2337/dc13-1414

Longitudinally extensive varicella-zoster virus myelitis in a patient with multiple sclerosis.
From the Departments of *Neurology; and †Radiology, Hospital General Universitario Gregorio Marañón, Madrid, Spain; and ‡Serology Section, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.: Cuello JP, Romero J, de Ory F, de Andrés C.
Spine (Phila Pa 1976). 2013 Sep 15;38(20)

To report this rare varicella-zoster virus (VZV) complication in a patient with multiple sclerosis. 
Awareness of the potentially varied presentation of VZV myelitis can enable earlier recognition and specific treatment.