Monday, May 12


Numbness and Tingling as a Symptom of Multiple Sclerosis. 
Parasthesia Can Affect Quality of Life

The fumaric acid ester BG-12: a new option in MS therapy.
Expert Rev Neurother. 2013 Aug 14. [Epub ahead of print]
Department of Neurology, University of Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany.

13 Early Signs & Symptoms of Multiple Sclerosis
Detecting the signs of multiple sclerosis early can help prevent its progression. Learn how to identify and respond to the symptoms of multiple sclerosis

Mechanical energy expenditure of subject with multiple sclerosis engaged in daily activities: a case study.
a Laboratoire APERE , Université de Picardie Jules Verne , EA-3300, UFR-STAPS, Amiens , France.

Pharmaceutical approval update
Dimethyl fumarate capsules (Tecfidera) for multiple sclerosis and ospemifene tablets (Osphena) for painful intercourse in postmenopausal women.

Study debunks controversial multiple sclerosis theory
There is no evidence that impaired blood flow or blockage in the veins of the neck or head is involved in multiple sclerosis

Headaches in multiple sclerosis patients might imply an inflammatorial process.
Institute of Medical Psychology and Medical Sociology, Medical Faculty, University of Rostock, Rostock, Germany ; Department of Neurology, Medical Faculty, University of Rostock, Rostock, Ger

Pathological correlates of magnetic resonance imaging texture heterogeneity in multiple sclerosis.
Department of Radiology, University of Calgary, Calgary, Alberta; Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta; Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta.
Ann Neurol. 2013 Feb 11. doi: 10.1002/ana.23867. [Epub ahead of print]
Diffusion tensor imaging detects treatment effects of FTY720 in experimental autoimmune encephalomyelitis mice.
Department of Chemistry, Washington University, St. Louis, MO, USA.
NMR Biomed. 2013 Aug 13. doi: 10.1002/nbm.3012. [Epub ahead of print]

Texas A&M Researchers Find New Clues To Attack Multiple Sclerosis

P023 Observational Drug Therapy Trials Add Up Useful Information As Compared With Randomised Controlled Trials: Case Multiple Sclerosis
BMJ Qual.  Saf. 2013;  22(Suppl_1): p. 45-a

Transient autoimmune hyperthyroidism following the withdrawal of Tysabri (Natalizumab) in patients with multiple sclerosis.
Neurol Sci. 2013 Aug 13. [Epub ahead of print]
Multiple Sclerosis Unit, Department of Neurology, Hospital General Universitario de Valencia, Valencia, Spain,

Environmental factors associated with disease progression after the first demyelinating event: results from the multi-center SET study.
Department of Neurology and Center of Clinical Neuroscience, 1st Faculty of Medicine and General University Hospital, Charles University, Prague, Czech Republic.

PGE2 contributes to in vitro MSC-mediated inhibition of non-specific- and antigen-specific T cells proliferation in MS patients.
Belarusian Medical Academy of Post-Graduate Education, Minsk, Republic of Belarus.

Post-acute serum eosinophil and neutrophil-associated cytokine/chemokine profile can distinguish between patients with neuromyelitis optica and multiple sclerosis; and identifies potential pathophysiological mechanisms - A pilot study.
The Walton Centre NHS Foundation Trust, Lower Lane, Fazakerly, Liverpool, UK; The Institute of Infection and Global Health, West Derby Street, University of Liverpool, UK.
Cytokine. 2013 Aug 10. pii: S1043-4666(13)00634-0. doi: 10.1016/j.cyto.2013.07.019. [Epub ahead of print]

Functional neuroimaging may quantify spinal cord demyelinating disease.
Neurology. 2013 Jun 11;80(24):2207. doi: 10.1212/WNL.0b013e318296ea5b. Epub 2013 May 10.

Quantitative MRI and ultrastructural examination of the cuprizone mouse model of demyelination.
NMR Biomed. 2013 Aug 13. doi: 10.1002/nbm.2992. [Epub ahead of print]
Department of Physics and Astronomy, University of Manitoba, Winnipeg, MB, Canada; Department of Radiology, University of Manitoba, Winnipeg, MB, Canada.

Systematic Review of the Epidemiology of Urinary Incontinence and Detrusor Overactivity among Patients with Neurogenic Overactive Bladder.
Service Urologie, Centre Hospitalier Lyon Sud, Pierre-Bénite, France.
Neuroepidemiology. 2013 Aug 8;41(3-4):146-155. [Epub ahead of print]

Optic neuritis is associated with inner nuclear layer thickening and microcystic macular edema independently of multiple sclerosis.
NeuroCure Clinical Research Center and Experimental and Clinical Research Center, Charité - Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine, Berlin, Germany.

Use of botulinum toxin in individuals with neurogenic detrusor overactivity: State of the art review.
Kessler Institute for Rehabilitation, West Orange, NJ, USA; Rutgers New Jersey Medical School, Newark, NJ, USA; Kessler Foundation, West Orange, NJ, USA.
J Spinal Cord Med. 2013 Sep;36(5):402-19. doi: 10.1179/2045772313Y.0000000116.

Aquaporin-4 antibody-negative neuromyelitis optica: distinct assay sensitivity-dependent entity.
NOMADMUS Study Group.
Lyon's Neuroscience Research Center, Team ONCOFLAM, Inserm U 1028/CNRS 5292, Lyon, France.

Brain characterization using normalized quantitative magnetic resonance imaging.
Center for Medical Image Science and Visualization, CMIV, Linköping University, Linköping, Sweden ; Clinical Physiology, Department of Medical and Health Sciences, Linköping University, Department of Clin

A&W Rendez-vous to end MS: On Thursday, August 22, support the Multiple Sclerosis Society of Canada

Canadian study finds no blocked neck veins in MS patients
A long-awaited Canadian study has found no evidence that blocked neck veins or impaired blood flow are connected with multiple sclerosis,