Monday, May 12

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HERE'S 156 STUDIES AND ARTICLES WE POSTED FOR YOU LAST WEEK:

Sativex oro-mucosal spray
GW Pharma has submitted a phase III investigational new drug application with the  FDA to conduct a Sativex efficacy and safety clinical program to treat spasticity due to Multiple Sclerosis. Sativex has been undergoing phase III program in the US as a treatment for Cancer pain
Composed mainly of two cannabinoids including CBD (cannabidiol,) and THC (delta 9 tetrahydrocannabinol), Sativex is administered as a metered dose oro-mucosal spray.

Impact of of wheelchair use on quality of life
Are you ready for a wheelchair? It may improve your quality of life
Firefighter Arsonist Gets Home Detention Not Prison. The Columbia firefighter, whose kids wept, has MS, and begged the judge for mercy.
Daye "had a life that was 99 percent good and 1 percent not," Li told Hood. Li also offered medical evidence on the effects of multiple sclerosis on Daye, letting ...

Seizure Disorders Enter Medical Marijuana Debate
The role of cannabinoids in the treatment of seizure disorders in children has come under the spotlight in recent months amid a string of media reports of parents obtaining the substances in states where medical marijuana is now legal and claiming "miraculous" reductions in seizures with the treatment.

Patients have faith in MS theory despite findings of McMaster study
Mary Jacobs walked again, and that is all the proof her husband needs to believe in a radical theory that multiple sclerosis is related to narrowed veins in the ...

 Medical cannabis needed 'as soon as possible'
People suffering with multiple sclerosis are “extremely frustrated and tired” of waiting for the legalisation of medicinal cannabis, MS Ireland has said

Ford Unveils 2013 Woodward Dream Cruise Charity Car
This car, made specifically for the 2013 Woodward Dream Cruise, will be auctioned off. Proceeds will go to the National Multiple Sclerosis Society

Raising sails in Casco Bay and raising money for worthwhile cause
MS Harborfest Weekend includes a sailboat parade, sailing races, lobster boat races and a tugboat

Personal care assistants divided by union question
Mark Kirwin cares for his wife, Christine, at home, where her multiple sclerosis requires he get help from nurses and use a lot of ...

The fumaric acid ester BG-12: a new option in MS therapy.
Expert Rev Neurother. 2013 Aug 14. [Epub ahead of print]
Department of Neurology, University of Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany.

13 Early Signs & Symptoms of Multiple Sclerosis
Detecting the signs of multiple sclerosis early can help prevent its progression. Learn how to identify and respond to the symptoms of multiple sclerosis

Mechanical energy expenditure of subject with multiple sclerosis engaged in daily activities: a case study.
a Laboratoire APERE , Université de Picardie Jules Verne , EA-3300, UFR-STAPS, Amiens , France.

Pharmaceutical approval update
Dimethyl fumarate capsules (Tecfidera) for multiple sclerosis and ospemifene tablets (Osphena) for painful intercourse in postmenopausal women.

Study debunks controversial multiple sclerosis theory
There is no evidence that impaired blood flow or blockage in the veins of the neck or head is involved in multiple sclerosis

Headaches in multiple sclerosis patients might imply an inflammatorial process.
Institute of Medical Psychology and Medical Sociology, Medical Faculty, University of Rostock, Rostock, Germany ; Department of Neurology, Medical Faculty, University of Rostock, Rostock, Ger

Pathological correlates of magnetic resonance imaging texture heterogeneity in multiple sclerosis.
Department of Radiology, University of Calgary, Calgary, Alberta; Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta; Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta.
Ann Neurol. 2013 Feb 11. doi: 10.1002/ana.23867. [Epub ahead of print]
Diffusion tensor imaging detects treatment effects of FTY720 in experimental autoimmune encephalomyelitis mice.
Department of Chemistry, Washington University, St. Louis, MO, USA.
NMR Biomed. 2013 Aug 13. doi: 10.1002/nbm.3012. [Epub ahead of print]

Texas A&M Researchers Find New Clues To Attack Multiple Sclerosis

P023 Observational Drug Therapy Trials Add Up Useful Information As Compared With Randomised Controlled Trials: Case Multiple Sclerosis
BMJ Qual.  Saf. 2013;  22(Suppl_1): p. 45-a

Transient autoimmune hyperthyroidism following the withdrawal of Tysabri (Natalizumab) in patients with multiple sclerosis.
Neurol Sci. 2013 Aug 13. [Epub ahead of print]
Multiple Sclerosis Unit, Department of Neurology, Hospital General Universitario de Valencia, Valencia, Spain,

Environmental factors associated with disease progression after the first demyelinating event: results from the multi-center SET study.
Department of Neurology and Center of Clinical Neuroscience, 1st Faculty of Medicine and General University Hospital, Charles University, Prague, Czech Republic.

PGE2 contributes to in vitro MSC-mediated inhibition of non-specific- and antigen-specific T cells proliferation in MS patients.
Belarusian Medical Academy of Post-Graduate Education, Minsk, Republic of Belarus.

Post-acute serum eosinophil and neutrophil-associated cytokine/chemokine profile can distinguish between patients with neuromyelitis optica and multiple sclerosis; and identifies potential pathophysiological mechanisms - A pilot study.
The Walton Centre NHS Foundation Trust, Lower Lane, Fazakerly, Liverpool, UK; The Institute of Infection and Global Health, West Derby Street, University of Liverpool, UK.
Cytokine. 2013 Aug 10. pii: S1043-4666(13)00634-0. doi: 10.1016/j.cyto.2013.07.019. [Epub ahead of print]

Functional neuroimaging may quantify spinal cord demyelinating disease.
Neurology. 2013 Jun 11;80(24):2207. doi: 10.1212/WNL.0b013e318296ea5b. Epub 2013 May 10.

Quantitative MRI and ultrastructural examination of the cuprizone mouse model of demyelination.
NMR Biomed. 2013 Aug 13. doi: 10.1002/nbm.2992. [Epub ahead of print]
Department of Physics and Astronomy, University of Manitoba, Winnipeg, MB, Canada; Department of Radiology, University of Manitoba, Winnipeg, MB, Canada.

Systematic Review of the Epidemiology of Urinary Incontinence and Detrusor Overactivity among Patients with Neurogenic Overactive Bladder.
Service Urologie, Centre Hospitalier Lyon Sud, Pierre-Bénite, France.
Neuroepidemiology. 2013 Aug 8;41(3-4):146-155. [Epub ahead of print]

Optic neuritis is associated with inner nuclear layer thickening and microcystic macular edema independently of multiple sclerosis.
NeuroCure Clinical Research Center and Experimental and Clinical Research Center, Charité - Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine, Berlin, Germany.

Use of botulinum toxin in individuals with neurogenic detrusor overactivity: State of the art review.
Kessler Institute for Rehabilitation, West Orange, NJ, USA; Rutgers New Jersey Medical School, Newark, NJ, USA; Kessler Foundation, West Orange, NJ, USA.
J Spinal Cord Med. 2013 Sep;36(5):402-19. doi: 10.1179/2045772313Y.0000000116.

Aquaporin-4 antibody-negative neuromyelitis optica: distinct assay sensitivity-dependent entity.
NOMADMUS Study Group.
Lyon's Neuroscience Research Center, Team ONCOFLAM, Inserm U 1028/CNRS 5292, Lyon, France. romain.marignier@chu-lyon.fr

Brain characterization using normalized quantitative magnetic resonance imaging.
Center for Medical Image Science and Visualization, CMIV, Linköping University, Linköping, Sweden ; Clinical Physiology, Department of Medical and Health Sciences, Linköping University, Department of Clin

A&W Rendez-vous to end MS: On Thursday, August 22, support the Multiple Sclerosis Society of Canada

Canadian study finds no blocked neck veins in MS patients
A long-awaited Canadian study has found no evidence that blocked neck veins or impaired blood flow are connected with multiple sclerosis,

Numbness and Tingling as a Symptom of Multiple Sclerosis. 
Parasthesia Can Affect Quality of Life

The fumaric acid ester BG-12: a new option in MS therapy.
Expert Rev Neurother. 2013 Aug 14. [Epub ahead of print]
Department of Neurology, University of Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany.

13 Early Signs & Symptoms of Multiple Sclerosis
Detecting the signs of multiple sclerosis early can help prevent its progression. Learn how to identify and respond to the symptoms of multiple sclerosis

Mechanical energy expenditure of subject with multiple sclerosis engaged in daily activities: a case study.
a Laboratoire APERE , Université de Picardie Jules Verne , EA-3300, UFR-STAPS, Amiens , France.

Pharmaceutical approval update
Dimethyl fumarate capsules (Tecfidera) for multiple sclerosis and ospemifene tablets (Osphena) for painful intercourse in postmenopausal women.

Study debunks controversial multiple sclerosis theory
There is no evidence that impaired blood flow or blockage in the veins of the neck or head is involved in multiple sclerosis

Headaches in multiple sclerosis patients might imply an inflammatorial process.
Institute of Medical Psychology and Medical Sociology, Medical Faculty, University of Rostock, Rostock, Germany ; Department of Neurology, Medical Faculty, University of Rostock, Rostock, Ger

Pathological correlates of magnetic resonance imaging texture heterogeneity in multiple sclerosis.
Department of Radiology, University of Calgary, Calgary, Alberta; Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta; Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta.
Ann Neurol. 2013 Feb 11. doi: 10.1002/ana.23867. [Epub ahead of print]
Diffusion tensor imaging detects treatment effects of FTY720 in experimental autoimmune encephalomyelitis mice.
Department of Chemistry, Washington University, St. Louis, MO, USA.
NMR Biomed. 2013 Aug 13. doi: 10.1002/nbm.3012. [Epub ahead of print]

Texas A&M Researchers Find New Clues To Attack Multiple Sclerosis

P023 Observational Drug Therapy Trials Add Up Useful Information As Compared With Randomised Controlled Trials: Case Multiple Sclerosis
BMJ Qual.  Saf. 2013;  22(Suppl_1): p. 45-a

Transient autoimmune hyperthyroidism following the withdrawal of Tysabri (Natalizumab) in patients with multiple sclerosis.
Neurol Sci. 2013 Aug 13. [Epub ahead of print]
Multiple Sclerosis Unit, Department of Neurology, Hospital General Universitario de Valencia, Valencia, Spain,

Environmental factors associated with disease progression after the first demyelinating event: results from the multi-center SET study.
Department of Neurology and Center of Clinical Neuroscience, 1st Faculty of Medicine and General University Hospital, Charles University, Prague, Czech Republic.

PGE2 contributes to in vitro MSC-mediated inhibition of non-specific- and antigen-specific T cells proliferation in MS patients.
Belarusian Medical Academy of Post-Graduate Education, Minsk, Republic of Belarus.

Post-acute serum eosinophil and neutrophil-associated cytokine/chemokine profile can distinguish between patients with neuromyelitis optica and multiple sclerosis; and identifies potential pathophysiological mechanisms - A pilot study.
The Walton Centre NHS Foundation Trust, Lower Lane, Fazakerly, Liverpool, UK; The Institute of Infection and Global Health, West Derby Street, University of Liverpool, UK.
Cytokine. 2013 Aug 10. pii: S1043-4666(13)00634-0. doi: 10.1016/j.cyto.2013.07.019. [Epub ahead of print]

Functional neuroimaging may quantify spinal cord demyelinating disease.
Neurology. 2013 Jun 11;80(24):2207. doi: 10.1212/WNL.0b013e318296ea5b. Epub 2013 May 10.

Quantitative MRI and ultrastructural examination of the cuprizone mouse model of demyelination.
NMR Biomed. 2013 Aug 13. doi: 10.1002/nbm.2992. [Epub ahead of print]
Department of Physics and Astronomy, University of Manitoba, Winnipeg, MB, Canada; Department of Radiology, University of Manitoba, Winnipeg, MB, Canada.

Systematic Review of the Epidemiology of Urinary Incontinence and Detrusor Overactivity among Patients with Neurogenic Overactive Bladder.
Service Urologie, Centre Hospitalier Lyon Sud, Pierre-Bénite, France.
Neuroepidemiology. 2013 Aug 8;41(3-4):146-155. [Epub ahead of print]

Optic neuritis is associated with inner nuclear layer thickening and microcystic macular edema independently of multiple sclerosis.
NeuroCure Clinical Research Center and Experimental and Clinical Research Center, Charité - Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine, Berlin, Germany.

Use of botulinum toxin in individuals with neurogenic detrusor overactivity: State of the art review.
Kessler Institute for Rehabilitation, West Orange, NJ, USA; Rutgers New Jersey Medical School, Newark, NJ, USA; Kessler Foundation, West Orange, NJ, USA.
J Spinal Cord Med. 2013 Sep;36(5):402-19. doi: 10.1179/2045772313Y.0000000116.

Aquaporin-4 antibody-negative neuromyelitis optica: distinct assay sensitivity-dependent entity.
NOMADMUS Study Group.
Lyon's Neuroscience Research Center, Team ONCOFLAM, Inserm U 1028/CNRS 5292, Lyon, France. romain.marignier@chu-lyon.fr

Brain characterization using normalized quantitative magnetic resonance imaging.
Center for Medical Image Science and Visualization, CMIV, Linköping University, Linköping, Sweden ; Clinical Physiology, Department of Medical and Health Sciences, Linköping University, Department of Clin

A&W Rendez-vous to end MS: On Thursday, August 22, support the Multiple Sclerosis Society of Canada

Canadian study finds no blocked neck veins in MS patients
A long-awaited Canadian study has found no evidence that blocked neck veins or impaired blood flow are connected with multiple sclerosis,

Numbness and Tingling as a Symptom of Multiple Sclerosis. 
Parasthesia Can Affect Quality of Life

The fumaric acid ester BG-12: a new option in MS therapy.
Expert Rev Neurother. 2013 Aug 14. [Epub ahead of print]
Department of Neurology, University of Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany.

13 Early Signs & Symptoms of Multiple Sclerosis
Detecting the signs of multiple sclerosis early can help prevent its progression. Learn how to identify and respond to the symptoms of multiple sclerosis



Mechanical energy expenditure of subject with multiple sclerosis engaged in daily activities: a case study.
a Laboratoire APERE , Université de Picardie Jules Verne , EA-3300, UFR-STAPS, Amiens , France.

Pharmaceutical approval update
Dimethyl fumarate capsules (Tecfidera) for multiple sclerosis and ospemifene tablets (Osphena) for painful intercourse in postmenopausal women.

Study debunks controversial multiple sclerosis theory
There is no evidence that impaired blood flow or blockage in the veins of the neck or head is involved in multiple sclerosis

Headaches in multiple sclerosis patients might imply an inflammatorial process.
Institute of Medical Psychology and Medical Sociology, Medical Faculty, University of Rostock, Rostock, Germany ; Department of Neurology, Medical Faculty, University of Rostock, Rostock, Ger

Pathological correlates of magnetic resonance imaging texture heterogeneity in multiple sclerosis.
Department of Radiology, University of Calgary, Calgary, Alberta; Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta; Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta.
Ann Neurol. 2013 Feb 11. doi: 10.1002/ana.23867. [Epub ahead of print]
Diffusion tensor imaging detects treatment effects of FTY720 in experimental autoimmune encephalomyelitis mice.
Department of Chemistry, Washington University, St. Louis, MO, USA.
NMR Biomed. 2013 Aug 13. doi: 10.1002/nbm.3012. [Epub ahead of print]

Texas A&M Researchers Find New Clues To Attack Multiple Sclerosis

P023 Observational Drug Therapy Trials Add Up Useful Information As Compared With Randomised Controlled Trials: Case Multiple Sclerosis
BMJ Qual.  Saf. 2013;  22(Suppl_1): p. 45-a

Transient autoimmune hyperthyroidism following the withdrawal of Tysabri (Natalizumab) in patients with multiple sclerosis.
Neurol Sci. 2013 Aug 13. [Epub ahead of print]
Multiple Sclerosis Unit, Department of Neurology, Hospital General Universitario de Valencia, Valencia, Spain,

Environmental factors associated with disease progression after the first demyelinating event: results from the multi-center SET study.
Department of Neurology and Center of Clinical Neuroscience, 1st Faculty of Medicine and General University Hospital, Charles University, Prague, Czech Republic.

PGE2 contributes to in vitro MSC-mediated inhibition of non-specific- and antigen-specific T cells proliferation in MS patients.
Belarusian Medical Academy of Post-Graduate Education, Minsk, Republic of Belarus.

Post-acute serum eosinophil and neutrophil-associated cytokine/chemokine profile can distinguish between patients with neuromyelitis optica and multiple sclerosis; and identifies potential pathophysiological mechanisms - A pilot study.
The Walton Centre NHS Foundation Trust, Lower Lane, Fazakerly, Liverpool, UK; The Institute of Infection and Global Health, West Derby Street, University of Liverpool, UK.
Cytokine. 2013 Aug 10. pii: S1043-4666(13)00634-0. doi: 10.1016/j.cyto.2013.07.019. [Epub ahead of print]

Functional neuroimaging may quantify spinal cord demyelinating disease.
Neurology. 2013 Jun 11;80(24):2207. doi: 10.1212/WNL.0b013e318296ea5b. Epub 2013 May 10.

Quantitative MRI and ultrastructural examination of the cuprizone mouse model of demyelination.
NMR Biomed. 2013 Aug 13. doi: 10.1002/nbm.2992. [Epub ahead of print]
Department of Physics and Astronomy, University of Manitoba, Winnipeg, MB, Canada; Department of Radiology, University of Manitoba, Winnipeg, MB, Canada.

Systematic Review of the Epidemiology of Urinary Incontinence and Detrusor Overactivity among Patients with Neurogenic Overactive Bladder.
Service Urologie, Centre Hospitalier Lyon Sud, Pierre-Bénite, France.
Neuroepidemiology. 2013 Aug 8;41(3-4):146-155. [Epub ahead of print]

Optic neuritis is associated with inner nuclear layer thickening and microcystic macular edema independently of multiple sclerosis.
NeuroCure Clinical Research Center and Experimental and Clinical Research Center, Charité - Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine, Berlin, Germany.

Use of botulinum toxin in individuals with neurogenic detrusor overactivity: State of the art review.
Kessler Institute for Rehabilitation, West Orange, NJ, USA; Rutgers New Jersey Medical School, Newark, NJ, USA; Kessler Foundation, West Orange, NJ, USA.
J Spinal Cord Med. 2013 Sep;36(5):402-19. doi: 10.1179/2045772313Y.0000000116.

Aquaporin-4 antibody-negative neuromyelitis optica: distinct assay sensitivity-dependent entity.
NOMADMUS Study Group.
Lyon's Neuroscience Research Center, Team ONCOFLAM, Inserm U 1028/CNRS 5292, Lyon, France. romain.marignier@chu-lyon.fr

Brain characterization using normalized quantitative magnetic resonance imaging.
Center for Medical Image Science and Visualization, CMIV, Linköping University, Linköping, Sweden ; Clinical Physiology, Department of Medical and Health Sciences, Linköping University, Department of Clin

A&W Rendez-vous to end MS: On Thursday, August 22, support the Multiple Sclerosis Society of Canada

Canadian study finds no blocked neck veins in MS patients
A long-awaited Canadian study has found no evidence that blocked neck veins or impaired blood flow are connected with multiple sclerosis,

 Surgery and Risk for Multiple Sclerosis
... that a prior history of surgery may be associated with subsequent risk for developing multiple sclerosis? This systemic review evaluated the risk.
Journal Article, BMC Neurol, August 2013

Adding a Drug Helps Overactive Bladder
Published: Aug 14, 2013 | Updated: Aug 14, 2013

Fingolimod Therapy for Multiple Sclerosis
The use of fingolimod therapy for multiple sclerosis has been limited by concerns for its safety, especially regarding cardiac effects. What do you need to know...
Journal Article, Semin Neurol, July 2013

Transient autoimmune hyperthyroidism following the withdrawal of Natalizumab in patients with multiple sclerosis.
Neurol Sci. 2013 Aug 13. [Epub ahead of print]
Multiple Sclerosis Unit, Department of Neurology, Hospital General Universitario de Valencia, Valencia, Spain, marida.c@hotmail.com.
PMID: 23942788 [PubMed - as supplied by publisher]

Systematic Review of the Epidemiology of Urinary Incontinence and Detrusor Overactivity among Patients with Neurogenic Overactive Bladder.
Neuroepidemiology. 2013 Aug 8;41(3-4):146-155. [Epub ahead of print]
Service Urologie, Centre Hospitalier Lyon Sud, Pierre-Bénite, France.

Quantitative MRI and ultrastructural examination of the cuprizone mouse model of demyelination.
NMR Biomed. 2013 Aug 13. doi: 10.1002/nbm.2992. [Epub ahead of print]Department of Physics and Astronomy, University of Manitoba, Winnipeg, MB, Canada; Department of Radiology, University of Manitoba, Winnipeg, MB, Canada.

Cerebrospinal Fluid Oligoclonal Bands in Multiple Sclerosis and Clinically Isolated Syndromes.
Journal Article, J Neurol Neurosurg Psychiatry, August 2013

Immune competence after alemtuzumab treatment of multiple sclerosis.
From the Department of Clinical Neurosciences (C.L.M., O.T., D.A.S.C., A.J.C., J.L.J.), University of Cambridge; and Department of Clinical Immunology (D.S.K.), Addenbrooke's Hospital, Cambridge, UK.

STEM CELLS: The Tisch MS Research Center of New York announced it has received Investigational New Drug approval from the FDA to commence a Phase 1 trial using autologous neural stem cells in the treatment of multiple sclerosis 
GW Pharmaceuticals plc Opens an Investigational New Drug Application in the United States for a Sativex® Phase 3 Clinical Program as a Treatment for Spasticity Due to Multiple Sclerosis
Sativex is an investigational new product composed primarily of two cannabinoids: CBD (cannabidiol,) and THC

 Gene-vitamin D interactions likely to influence pathogenesis and risk of relapse in multiple sclerosis.
Nat Rev Neurol. 2013 Aug 13. doi: 10.1038/nrneurol.2013.160.

Opexa Therapeutics, Inc., a biotechnology company developing Tcelna(R) , a novel T-cell therapy for multiple sclerosis (MS), today reported financial results

MS blocked vein theory disputed in Canadian study. Evidence mounts against Zamboni's multiple sclerosis idea
CBC News

The glutathione S-transferase T1 deletion is associated with susceptibility to multiple sclerosis.
Zivković M, Zivotić I, Dinčić E, Stojković L, Vojinović S, Stanković A.

Multiple sclerosis patients see "rapid expansion" of effective new treatment options according to a review article in the journal Neurologic Clinics.

Multiple Sclerosis and MRIs: The Results 
ChicagoNow

Multiple Sclerosis and Exercise Trial Now Enrolling

Plasma levels of neuron specific enolase quantifies the extent of neuronal injury in murine models of ischemic stroke and multiple sclerosis.
Neurobiol Dis. 2013 Aug 8.

 Using observational analysis of multiple sclerosis relapse to design outcomes-based contracts for disease-modifying drugs: a feasibility assessment.
 Med Econ. 2013 Aug 8. [Epub ahead of print]


Multiple sclerosis presenting initially with a worsening of migraine symptoms.
J Headache Pain. 2013 Aug 9;14(1):70. [Epub ahead of print]

Multiple sclerosis: Regenerative therapies for MS-hope on the horizon.
Nat Rev Neurol. 2013 Aug 13. doi: 10.1038/nrneurol.2013.158. [Epub ahead of print]

Multiple sclerosis: Month of birth effect in MS-fact or artefact?
Nat Rev Neurol. 2013 Aug 13. doi: 10.1038/nrneurol.2013.156. [Epub ahead of print]
MS Centre ErasMS, Department of Neurology, Erasmus MC, PO Box 2040, 3000 CA Rotterdam,

Headaches in multiple sclerosis patients might imply an inflammatorial process.
Institute of Medical Psychology and Medical Sociology, Medical Faculty, University of Rostock, Rostock, Germany ; Department of Neurology, Medical Faculty, University of Rostock, Rostock, Germany.

The effectiveness of aerobic training, cognitive behavioural therapy, and energy conservation management in treating MS-related fatigue: the design of the TREFAMS-ACE programme.
Trials. 2013 Aug 12;14(1):250. [Epub ahead of print]

Optic neuritis is associated with inner nuclear layer thickening and microcystic macular edema independently of multiple sclerosis.
NeuroCure Clinical Research Center and Experimental and Clinical Research Center, Charité - Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine, Berlin, Germany.

Pathological correlates of magnetic resonance imaging texture heterogeneity in multiple sclerosis.
Zhang Y, Moore GR, Laule C, Bjarnason TA, Kozlowski P, Traboulsee A, Li DK.
Department of Radiology, University of Calgary, Calgary, Alberta; Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta; Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta.

Multiple sclerosis: Gene-vitamin D interactions likely to influence pathogenesis and risk of relapse in multiple sclerosis.
Nat Rev Neurol. 2013 Aug 13. doi: 10.1038/nrneurol.2013.160. [Epub ahead of print]

Establishment of monoclonal antibodies against the extracellular domain that block binding of NMO-IgG to AQP4.
J Neuroimmunol. 2013 Jul 15;260(1-2):107-16. doi: 10.1016/j.jneuroim.2013.03.003.Department of Pharmacology, School of Medicine, Keio University, 35 Shinanomachi, Shinjyuku-ku, Tokyo 160-8582, Japan.

Modeling of cognitive impairment by disease duration in multiple sclerosis: a cross-sectional study.
Multiple Sclerosis Center, Sheba Medical Center, Tel-Hashomer, Israel ; Neurology Department, Sheba Medical Center, Tel-Hashomer, Israel ; Sackler School of Medicine, Tel-Aviv University, Tel Aviv, Israel.

Cognitive and Clinical Dysfunction, Altered MEG Resting-State Networks and Thalamic Atrophy in Multiple Sclerosis.
Department of Neurology, VU University Medical Center, Amsterdam, The Netherlands ; Department of Clinical Neurophysiology and Magnetoencephalography Center, VU University Medical Center, Amsterdam, The Netherlands.

Correction: Characterization of Microcirculation in Multiple Sclerosis Lesions by Dynamic Texture Parameter Analysis (DTPA).
PLoS One. 2013 Jul 30;8(7). doi: 10.1371/annotation/4f4fb8b4-6730-4134-95f7-6d694f0cfe95. Print 2013.

The effects of mental practice in neurological rehabilitation; a systematic review and meta-analysis.
Front Hum Neurosci. 2013 Aug 2;7:390. doi: 10.3389/fnhum.2013.00390. Print 2013.
Research Centre Autonomy and Participation of Patients with a Chronic Illness, Zuyd University of Applied Sciences Heerlen, Netherlands ; School for Public Health and Primary Care (CAPHRI), Maastricht University Maastricht, Netherlands.

Cerebral venous thrombosis after high dose steroid in multiple sclerosis: a case report.
Department of Neurology, Karadeniz Technical University Medical Faculty, Trabzon, Turkey.
Hippokratia. 2013 Jan;17(1):88-90.

Body composition in multiple sclerosis.
Medical Department, Rehabilitation Center Amyntaio, General Hospital of Florina, Greece.

Perspectives of the relationship between IL-7 and autoimmune diseases.
Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, Anhui, 230032, People's Republic of China.

Th1 not Th17 cells drive spontaneous MS-like disease despite a functional regulatory T cell response.
Human Disease Immunogenetics Group, Section of Infectious Diseases and Immunity, Department of Medicine, Imperial College, Hammersmith Hospital, London, W12 0NN, UK.

Plasma homocysteine levels in patients with multiple sclerosis in the Greek population.
Department of Neurology, Athens National University, Aiginition Hospital, Athens, Greece.

Multimodal imaging of subventricular zone neural stem/progenitor cells in the cuprizone mouse model reveals increased neurogenic potential for the olfactory bulb pathway, but no contribution to remyelination of the corpus callosum.
Bio-Imaging Lab, University of Antwerp, Antwerp, Belgium.

Education attenuates the negative impact of traumatic brain injury on cognitive status.
Sumowski JF, Chiaravalloti N, Krch D, Paxton J, Deluca J.
Neuropsychology and Neuroscience, Kessler Foundation, West Orange, NJ; Department of Physical Medicine and Rehabilitation, UMDNJ -New Jersey Medical School, Newark, NJ. Electronic address: jsumowski@kesserfoundation.org.

Plasma levels of neuron specific enolase quantifies the extent of neuronal injury in murine models of ischemic stroke and multiple sclerosis.
Department of Neurology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany.

Multiple sclerosis. 
Am Fam Physician. 2013 May 15;87(10):712-3.
Imperial Healthcare Trust, London, United Kingdom.

Neurologists: The Last Bedside Physician-Scientists
Joseph R. Berger, MD.
JAMA Neurol. 2013;70(8):965 doi:10.1001/jamaneurol.2013.2977

Interleukin 17F Level and Interferon Beta Response in Patients With Multiple Sclerosis
Hans-Peter Hartung, MD, Lawrence Steinman, MD, Douglas S. Goodin, MD, et al.
JAMA Neurol. 2013;70(8):1017 doi:10.1001/jamaneurol.2013.192

The Neglected Neglect: Auditory Neglect
Sankalp Gokhale, MD, Sourabh Lahoti, MD, Louis R. Caplan, MD.
JAMA Neurol. 2013;70(8):1065 doi:10.1001/jamaneurol.2013.155

 Making Every Word Count for Nonresponsive Patients
Lorina Naci, PhD, Adrian M. Owen, PhD.
JAMA Neurol. Published online August 12, 2013. doi:10.1001/jamaneurol.2013.3686

Silver fillings and Multiple Sclerosis
Wisconsin State Journal
A recent post on the National Multiple Sclerosis Society LinkedIn site asked this question: Have any of you who are diagnosed with MS had your dental fillings containing mercury (mercury amalgam fillings) removed?

Efficacy and safety of laquinimod in multiple sclerosis: current status
   Shalom Haggiag, Serena Ruggieri, and Claudio Gasperini, MD, PhD
   Therapeutic Advances in Neurological Disorders. published 12 August
   2013, 10.1177/1756285613499424
   http://tan.sagepub.com/cgi/content/abstract/1756285613499424v1?ct=ct

Very low levels of education and cognitive reserve: A clinicopathologic study Jose Marcelo Farfel, Ricardo Nitrini, Claudia Kimie Suemoto, Lea
 Tenenholz Grinberg...
 Neurology August 13, 2013 81:650-657; published ahead of print July 19,  2013
 http://www.neurology.org/content/81/7/650.abstract.html?etoc

Head impulses in complete bilateral vestibular loss: Catch-up saccades require visual input
 Nadine Lehnen, Stefan Glasauer, Klaus Jahn, and Konrad P. Weber
 Neurology August 13, 2013 81:688-690; published ahead of print July 17, 2013
 http://www.neurology.org/content/81/7/688.extract.html?etoc

'loner' died of heart attack after learning to cope with Multiple Sclerosis...
This is Cornwall
A "LONER" from Newquay died of a heart attack after struggling to cope with multiple sclerosis (MS) for more than 20 years, an inquest has been told.

 With Disney trip, dream comes true for Kentwood girl with multiple ...
MLive.com
When she was 7, Kamor was diagnosed with multiple sclerosis. The disease attacks the central nervous system, causing inflammation and, at worst, death.

Multiple Sclerosis Society set to receive boost in funds from 101 mile ...
Home Care
Diagnosed with multiple sclerosis in 1998, James Pagram has taken to his mobility scooter to raise funds for the MS Society by embarking on a 101 mile ...

More research being done toward multiple sclerosis cure
Aiken Standard
Multiple sclerosis is a chronic, often disabling disease, according to the National MS Society. It starts in the central nervous system, an area composed of the ...

Free seminar on advances in the treatment of Multiple Sclerosis to ...
Plain Dealer
CLEVELAND, Ohio -- Learn about advances in the treatment of Multiple Sclerosis at a free Aug. 17 seminar at the Cleveland Marriott Downtown at Key Center.

"Secondary Progressive Multiple Sclerosis (SPMS) - Pipeline ...
This report provides information on the therapeutic development for Secondary Progressive Multiple Sclerosis (SPMS), complete with latest updates, and special ...

Women On The Move Meet Next Month In Briarcliff
The Daily Voice
Photo Credit: National Multiple Sclerosis Society ... on the Move Luncheon next month will raise money for multiple sclerosis and honor women philanthropists.

Your Health: The Importance of Exercise for those with Multiple Sclerosis
WSAW
This week, we hit the gym to learn the importance of working out for those with special conditions like Multiple Sclerosis. We spoke with Jon Swenson, ...


A Trial-Based Approach to Statin Guidelines
Paul M Ridker, MD, MPH, Peter W. F. Wilson, MD.
JAMA. Published online August 12, 2013. doi:10.1001/jama.2013.276529

 Contribution of cortical lesion subtypes at 7T MRI to physical and cognitive performance in MS
 A. Scott Nielsen, Revere P. Kinkel, Nancy Madigan, Emanuele Tinelli, Thomas Benner
 Neurology August 13, 2013 81:641-649; published ahead of print July 17, 2013
 http://www.neurology.org/content/81/7/641.abstract.html?etoc

  Rituximab review

IMPAIRED DECISION-MAKING AND DIFFUSION ORIENTATIONAL COMPLEXITY IN PEOPLE WITH MULTIPLE SCLEROSIS

Vitamin d: shining a light on clinical and sex specific effects in multiple sclerosis?

The relation between Vitamin D status with fatigue and depressive symptoms of multiple sclerosis.

Multiple Sclerosis Research: Chinese Medicine..Getting DMT is ...

 Mary Lahammer on living with multiple sclerosis: The feared disease a journalist lives with is no longer a death sentence.

Validity of the Dynamic Gait Index in People With Multiple Sclerosis


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