Monday, May 12

WEDNESDAY'S NEWS FOR DOCTORS & NURSES We posted 15 New Studies for Today: Wednesday

PLUS: 140 new Studies from 11/1 to Tuesday 11/12 Start at the Bottom: 

A decade of data for the uk multiple sclerosis risk-sharing scheme.

Respiratory tract rather than cutaneous atopic allergy inversely associate with multiple sclerosis: a case-control study.

Neuroborreliosis during natalizumab treatment in multiple sclerosis.

Impact of disease-modifying therapies on the survival of patients with multiple sclerosis in Taiwan, 1997-2008.
The results of this study support the notion that DMTs can improve the survival of patients with MS, and show that individuals with the risk factors of older age, rural residence and lower economic status had a higher MS-related mortality risk in Taiwan.

Detection of B-cell populations with monotypic light chain expression in cerebrospinal fluid specimens from patients with multiple sclerosis by polychromatic flow cytometry.

Preliminary study related the incidence of methylprednisolone pulse therapy in patients visited multiple sclerosis clinic located at the isfahan kashani hospital.

Effects of exercise training on fitness, mobility, fatigue, and health-related quality of life among adults with multiple sclerosis: a systematic review to inform guideline development.
Among those with mild to moderate disability from MS, there is sufficient evidence that exercise training is effective for improving both aerobic capacity and muscular strength. Exercise may improve mobility, fatigue, and health-related quality of life.

Incidence of multiple sclerosis in multiple racial and ethnic groups.
Our findings do not support the widely accepted assertion that blacks have a lower risk of MS than whites. A possible explanation for our findings is that people with darker skin tones have lower vitamin D levels and thereby an increased risk of MS, but this would not explain why Hispanics and Asians have a lower risk of MS than whites or why the higher risk of MS among blacks was found only among women.

Month of birth and risk of multiple sclerosis in a Portuguese population.

Squinting through layers of fog: assessing the cost effectiveness of treatments for multiple sclerosis.
There are many complexities for those designing and reporting cost-effectiveness studies of treatments for MS. Analysts, and ultimately decision makers, face multiple data and methodological challenges. Policy makers, technology developers, clinicians, patients and researchers need to acknowledge and address these challenges and to consider recommendations that will improve the current scenario. There is a need for further research that can constructively inform decision-making regarding the funding of treatments for MS.

Increased incidence of multiple sclerosis in the Veneto region, Italy.

A novel method for calculating prevalence of multiple sclerosis in Australia.

Newly diagnosed multiple sclerosis in state of Qatar.
MS in Qatar is an emerging disorder especially in the native population. The pattern of disease differs from other Middle Eastern countries by its milder clinical and aggressive radiologic disease presentation.

People with multiple sclerosis use many fall prevention strategies but still fall frequently.
People with MS who fall use more fall prevention strategies than those who do not fall.

Lung volume recruitment in multiple sclerosis.

Risk of multiple sclerosis following clinically isolated syndrome: a 4-year prospective study.
The aim of the study was to estimate the rate of conversion from clinically isolated syndrome (CIS) to multiple sclerosis (MS) and to investigate variables predicting conversion in a cohort of patients presenting with symptoms suggestive of MS. Patients with a first symptom suggestive of MS in the preceding 6 months and exclusion of other diseases were enrolled in an observational prospective study from December 2004 through June 2007.

140 STUDIES FROM 11/1 to Tuesday 11/12 are below: 

Advances in the treatment of relapsing—remitting multiple sclerosis — critical appraisal of fingolimod

How does fingolimod (gilenya(®)) fit in the treatment algorithm for highly active relapsing-remitting multiple sclerosis?

Adverse events during the titration phase of interferon-beta in remitting-relapsing multiple sclerosis are not predicted by body mass index nor by pharmacodynamic biomarkers

A pragmatic parallel arm multi-centre randomised controlled trial to assess the effectiveness and cost-effectiveness of a group-based fatigue management programme (FACETS) for people with multiple sclerosis.

Teriflunomide in relapsing multiple sclerosis: therapeutic utility.

Magnetic resonance monitoring of lesion evolution in multiple sclerosis.

The effect of fluoxetine on progression in progressive multiple sclerosis: a double-blind, randomized, placebo-controlled trial.

The effect of vitamin a supplementation on biochemical parameters in multiple sclerosis patients.

Updates on clinically isolated syndrome and diagnostic criteria for multiple sclerosis.

Epidemiology in multiple sclerosis: a pilgrim's progress.

[Multiple sclerosis and pregnancy].

Regional cortical thickness in relapsing remitting multiple sclerosis: A multi-center study.

Multicentre absolute myelin water content mapping: Development of a whole brain atlas and application to low-grade multiple sclerosis.

Improving the clinical correlation of multiple sclerosis black hole volume change by paired-scan analysis.

Mimotopic peptide immunotherapy for the treatment of multiple sclerosis, an inflammatory autoimmune disease.

P300 wave changes in patients with multiple sclerosis.

Is There Extra Cost of Institutional Care for MS Patients?

Adding to the burden: gastrointestinal symptoms and syndromes in multiple sclerosis.

Multiple cancers in a patient with systemic sclerosis and aggravated interstitial lung disease by chemotherapy.

Growth hormone response to clonidine administration for evaluation of autonomic dysfunction in multiple sclerosis patients.

Third ventricular enlargement in early stages of multiple sclerosis is a predictor of motor and neuropsychological deficits: a cross-sectional study.

Predictors of effectiveness of multidisciplinary rehabilitation treatment on motor dysfunction in multiple sclerosis.

Effects of exercise on fitness and cognition in progressive MS: a randomized, controlled pilot trial.

A Randomized, Double-Blind, Placebo-Controlled Trial of Duloxetine for the Treatment of Pain in Patients withMultiple Sclerosis.

Quality of life outcomes with BG-12 (dimethyl fumarate) in patients with relapsing-remitting multiple sclerosis: The DEFINE study.

Tolerability and pharmacokinetics of delayed-release dimethyl fumarate administered with and without aspirin in healthy volunteers.

BG-12 (dimethyl fumarate): a review of mechanism of action, efficacy, and safety.

Stress in multiple sclerosis: review of new developments and future directions.

Does pain in individuals with multiple sclerosis affect employment? A systematic review and meta-analysis.

Emerging injectable therapies for multiple sclerosis.

Aerobic exercise increases hippocampal volume and improves memory in multiple sclerosis: Preliminary findings.
Changes of brain resting state functional connectivity predict the persistence of cognitive rehabilitation effects in patients with multiple sclerosis.

Effect of textured insoles on balance and gait in people with multiple sclerosis: an exploratory trial.

Inflammation Markers in Multiple Sclerosis: CXCL16 Reflects and May Also Predict Disease Activity.

Increased breast cancer risk for patients with multiple sclerosis: a nationwide population-based cohort study.

Immunomodulatory and therapeutic effects of Hot-nature diet and co-supplemented hemp seed, evening primrose oils intervention in multiple sclerosis patients.

Measuring response in the gastrointestinal tract in systemic sclerosis.

Natalizumab (tysabri)-associated progressive multifocal leukoencephalopathy: insights from perfusion magnetic resonance imaging.

Placebo-controlled trial of oral laquinimod in multiple sclerosis: MRI evidence of an effect on brain tissue damage.

Disease-activity-free status in patients with relapsing-remitting multiple sclerosis treated with daclizumab high-yield process in the SELECT study.

Neuropsychological rehabilitation has beneficial effects on perceived cognitive deficits in multiple sclerosisduring nine-month follow-up.

The discovery of natalizumab, a potent therapeutic for multiple sclerosis

Immunoregulatory Effects of Interferon-β in Suppression of Th17 cells.

Quantification of multiple-sclerosis-related brain atrophy in two heterogeneous MRI datasets using mixed-effects modeling.

Intra-individual variability in information processing speed reflects white matter microstructure in multiple sclerosis.

Cognition in MS correlates with resting-state oscillatory brain activity: An explorative MEG source-space study.

OASIS is Automated Statistical Inference for Segmentation, with applications to multiple sclerosis lesion segmentation in MRI.

DTI detects water diffusion abnormalities in the thalamus that correlate with an extremity pain episode in a patient with multiple sclerosis.

A comprehensive approach to the segmentation of multichannel three-dimensional MR brain images in multiple sclerosis.

Regional cortical thickness in relapsing remitting multiple sclerosis: A multi-center study.

Multicentre absolute myelin water content mapping: Development of a whole brain atlas and application to low-grade multiple sclerosis.

Improving the clinical correlation of multiple sclerosis black hole volume change by paired-scan analysis.

Mimotopic peptide immunotherapy for the treatment of multiple sclerosis, an inflammatory autoimmune disease.

The changing landscape of voltage-gated calcium channels in neurovascular disorders and in neurodegenerative diseases.

Relative contribution of cognitive and physical disability components to quality of life in MS.

Improvement of driving skills in persons with Relapsing-Remitting Multiple Sclerosis: a pilot study.

Initial Immunopathogenesis of Multiple Sclerosis: Innate Immune Response.

TNFRSF1A in multiple sclerosis: A tale of soluble receptors and signaling cascades.

Clinically meaningful performance benchmarks in MS: Timed 25-Foot Walk and the real world.

A nine-year population-based cohort study on the risk of multiple sclerosis in patients with optic neuritis.

Mood and coping in clinically isolated syndrome and multiple sclerosis.

Alemtuzumab-Related Thyroid Dysfunction in a Phase 2 Trial of Patients with Relapsing-Remitting Multiple Sclerosis.

A single session of 1 mA anodal tDCS-supported motor training does not improve motor performance in patients with multiple sclerosis.

Regional brain atrophy and functional connectivity changes related to fatigue in multiple sclerosis.

Functional brain network analysis using minimum spanning trees in Multiple Sclerosis: An MEG source-space study.

Fatty fish intake is associated with decreased occurrence of multiple sclerosis.

Control of spasticity in a multiple sclerosis model using central nervous system-excluded CB1 cannabinoid receptor agonists 

Vowel Acoustics in Parkinson's Disease and Multiple Sclerosis: Comparison of Clear, Loud, and Slow Speaking Conditions

Predictors of effectiveness of multidisciplinary rehabilitation treatment on motor dysfunction in multiple sclerosis.

A Randomized, Double-Blind, Placebo-Controlled Trial of Duloxetine for the Treatment of Pain in Patients with Multiple Sclerosis.

Rare Inflammatory Diseases of the White Matter and Mimics of Multiple Sclerosis and Related Disorders.

Retinal Nerve Fiber Layer Thickness, Brain Atrophy, and Disability in Multiple Sclerosis Patients.

Reduced axonal motor protein expression in non-lesional grey matter in multiple sclerosis

HLA-E restricted CD8+ T cell subsets are phenotypically altered in multiple sclerosis patients 

Automated extraction of clinical traits of multiple sclerosis in electronic medical records

Quality of life outcomes with BG-12 (dimethyl fumarate) in patients with relapsing–remitting multiple sclerosis: The DEFINE study 

Early pathological alterations of lower lumber cords detected by ultrahigh-field MRI in a mouse multiple sclerosis model

The CYP27B1 variant associated with increased risk of autoimmune disease is underexpressed in tolerising dendritic cells.

Intraoperative smile in a multiple sclerosis patient with medication-refractory tremor.