FREE MS RESEARCH UPDATE: a comprehensive overview of research findings on all of the FDA-approved disease-modifying therapies, as well as many experimental treatments

This year's expanded MS Research Update incorporates new information about the approved disease-modifying therapies (DMTs), as well as numerous experimental drugs currently under investigation for the long-term treatment of multiple sclerosis (MS). Highlights and recent research results are provided for each drug. Please note that symptom-management drugs are not included in this report.
DOWNLOAD YOUR FREE PDF OR ORDER A FREE COPY

Will the anti-B-cell therapies (Rituximab) supplant Campath (alemtuzumab) and Tysabri (natalizumab) in MS?

"Rituximab is a B cell depleting agent that works in MS. The phase 2 results were spectacular and shifted the paradigm in MS. The anecdotal experience from the off-label use of rituximab in MS has confirmed this; I have personally used rituximab in a handful of cases and have been very impressed with its ability to switch-off disease activity."

"Due to complex, scientific and business, reasons Genentech-Roche decided against taking rituximab forward in MS. Instead they decided  to develop the follow-on compound ocrelizumab. This latter decision will delay the access of an anti-CD20 therapy for MSers by about 4 years.